NI License Manager versions 4.0 and later. Please be aware that Multisim does not run on Mac. We’ve been getting some questions about this from our customers, so we put together this post to help make the process easier. Of course, the first step to using your software is to install it. Because of its ease-of-use and prevalence in the industry, many higher education institutions teach it to their students. National Instruments Multisim is an industry standard circuit design and analysis program.